Small Benchtop Freeze-Drying Machine

Small Benchtop Freeze-Drying Machine

Benchtop freeze-drying machines perform controlled sublimation for small-batch laboratory samples, biological specimens, and pharmaceutical formulations. Engineered for space-constrained labs, these units integrate refrigeration, vacuum control, and heating systems into a single compact enclosure to ensure reproducible drying cycles for R&D and analytical preparation.
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Description
Technical Parameters

Benchtop freeze-drying machines perform controlled sublimation for small-batch laboratory samples, biological specimens, and pharmaceutical formulations. Engineered for space-constrained labs, these units integrate refrigeration, vacuum control, and heating systems into a single compact enclosure to ensure reproducible drying cycles for R&D and analytical preparation.

 

Product Range

 

 

Model Series

Condenser Temp

Ice Condenser Capacity

Shelf Dimensions

Primary Application

BT-50A (Standard)

-50°C

3 kg / 24h

200 x 300 mm (3 tiers)

Aqueous solutions, botanical extracts, general lab samples.

BT-80A (Deep-Cool)

-80°C

4 kg / 24h

200 x 300 mm (3 tiers)

Solvents with low eutectic points, peptides, antibiotics.

BT-TP (Top-Press)

-50°C / -80°C

3 kg / 24h

Pneumatic stoppering vial shelves

Pharmaceutical vial sealing under vacuum or inert gas.

 

Technical Specifications

 

 

 

Category

Technical Parameter

Model BT-50A (Standard)

Model BT-80A (Deep-Cool)

Model BT-TP (Top-Press)

Performance & Capacity

24-Hour Ice Condenser Capacity

>= 3 kg / 24h

>= 4 kg / 24h

>= 3 kg / 24h

 

Condenser Ultimate Temperature

-50°C (+/- 1°C)

-80°C (+/- 1°C)

-50°C / -80°C (Optional)

Shelving & Heating

Shelf Temperature Range

-40°C to +60°C

-40°C to +60°C

-40°C to +60°C

 

Shelf Temperature Uniformity

+/- 1°C (Active surface)

+/- 1°C (Active surface)

+/- 1°C (Active surface)

 

Shelf Dimensions & Count

200 x 300 mm (3 Tiers)

200 x 300 mm (3 Tiers)

Pneumatic stoppering shelves

Vacuum & Sensors

Ultimate Vacuum Pressure

< 5 Pa (Dry, unloaded)

< 5 Pa (Dry, unloaded)

< 5 Pa (Dry, unloaded)

 

Vacuum Measurement Sensor

Pirani Vacuum Sensor

Pirani Vacuum Sensor

Pirani Vacuum Sensor

Control & Interface

Control System Architecture

7-inch PLC Industrial Touchscreen

7-inch PLC Industrial Touchscreen

7-inch PLC Industrial Touchscreen

 

Program Memory

Up to 36 thermal/vacuum steps

Up to 36 thermal/vacuum steps

Up to 36 thermal/vacuum steps

Materials & Utilities

Chamber Construction

304 Stainless Steel (Cylindrical)

304 Stainless Steel (Cylindrical)

304 Stainless Steel (Cylindrical)

 

Refrigerant Type

CFC-Free (R404A / R23)

CFC-Free (R404A / R23)

CFC-Free (R404A / R23)

 

Electrical Supply

220V-240V, 50/60Hz, 1Ph

220V-240V, 50/60Hz, 1Ph

220V-240V, 50/60Hz, 1Ph

 

Defrost Method

Electric Heating Defrost

Electric Heating Defrost

Electric Heating Defrost

 

Applications

 

 

Pharmaceutical & Biotech R&D: Lyophilizing proteins, vaccines, enzymes, and diagnostic reagents to preserve bio-activity.


Chemistry & Material Science: Dehydrating nanomaterials, polymers, and catalysts without surface-tension collapse.


Food & Agricultural Science: Processing natural extracts and reference standards for compositional analysis.


Pathology & Preservation: Dehydrating biological tissues and samples without structural distortion.

 

Selection Guide

 

 

Solvent Eutectic Point: Select -50°C condensers for aqueous solutions. Select -80°C condensers for low-freezing-point solvents or organic mixtures (e.g., tert-butanol) to prevent meltback.


Moisture Load: Ensure 24-hour condenser capacity exceeds batch volume by at least 30%.


Vial Stoppering: Choose the Top-Press configuration for glass vials requiring vacuum or nitrogen sealing.


Chamber Geometry: Use manifold chambers for round-bottom flasks; use tray shelves for bulk powders and Petri dishes.

 

Customization Options

 

 

01/

Inert Gas Backfill Port: Integrated solenoid valve for Nitrogen (N2) or Argon post-drying filling.

02/

Eutectic Point Sensor: Resistance probe kit for real-time tray phase monitoring.

03/

Data Logging Software: RS485/Ethernet SCADA interface complying with FDA 21 CFR Part 11.

04/

Corrosion-Resistant Upgrade: PTFE-coated coils and hybrid vacuum pumps for aggressive solvents.

 

Quality Control

 

 

Leak Detection: Stainless steel chambers undergo helium mass spectrometer leak testing (< 10^-9 Pa*m^3/s).


Run Testing: Compressors undergo a 72-hour thermal stability test in a 35°C ambient chamber.


Electrical Inspection: Hipot dielectric testing and earth continuity checks performed per IEC 61010-1.


Traceability: Serial numbers and component calibration certificates logged in production database.

 

Packaging & International Shipping

 

 

Crate Construction: ISPM 15 heat-treated plywood crates with moisture barrier lining.


Internal Buffering: High-density molded EPE foam securing glass doors and HMI panels against shock.


Accessory Kit: Vacuum pump, silicone oil, KF-clamps, and manuals packed in a reinforced inner carton.


Shipping Terms: EXW, FOB, CIF, or DDP via air or ocean freight.

 

Technical Support & After-Sales Service

 

 

Documentation: English manuals, wiring schematics, P&ID diagrams, and IQ/OQ protocol templates supplied.


Remote Diagnostics: Ethernet port configuration for remote parameter troubleshooting.


Warranty: 12-month standard international warranty on non-consumable mechanical/electrical parts.


Spares Availability: Local stock of pump oil, door gaskets, and sensors for 48-hour dispatch.

 

Frequently Asked Questions

 

 

Q: Is the vacuum pump integrated or external?

A: External. It connects via standard KF25 bellows and quick-release clamps to isolate pump heat and vibration from the chamber.

Q: What is the required ambient operating temperature?

A: 15°C to 28°C (relative humidity < 80%). Maintain 30 cm clearance around ventilation grills.

Q: Can standard units handle organic solvents?

A: Standard units target aqueous solutions. Organic processing requires the Corrosion-Resistant option with PTFE coating.

Q: How is defrosting performed?

A: Built-in electric heating coils rapidly melt accumulated ice, discharging liquid via a bottom silicone drain tube.

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