Benchtop lyophilizers bridge sample preparation and pilot-scale production. Designed for thermal and vacuum precision, these units process organic tissues, biological formulations, and heat-sensitive chemical compounds. Core engineering emphasizes footprint efficiency, rapid batch turnover, and stable primary drying under strict vacuum thresholds to prevent eutectic melt or collapse.
Product Range
Three standardized configurations match specific throughput and thermal profiles:
|
Model Series |
Condenser Temp. |
Ice Capacity (24h) |
Shelf Area |
Primary Target |
|
BL-10A |
-50°C |
2 kg |
0.12 m² (2 Shelves) |
Standard biological samples, bacterial strains |
|
BL-18B |
-80°C |
4 kg |
0.18 m² (3 Shelves) |
Peptides, low eutectic point formulations |
|
BL-30C |
-80°C |
6 kg |
0.30 m² (4 Shelves) |
Pilot R&D, small-batch API production |
Technical Specifications
|
Technical Parameter |
BL-10A (Standard) |
BL-18B (Advanced) |
BL-30C (Pilot Scale) |
|
Condenser Temperature |
-50°C (±1°C stability) |
-80°C (±1°C stability) |
-80°C (±1°C stability) |
|
Ice Condensing Capacity |
2 kg / 24h |
4 kg / 24h |
6 kg / 24h |
|
Ultimate Vacuum Degree |
< 5 Pa (Unloaded via Pirani gauge) |
< 5 Pa (Unloaded via Pirani gauge) |
< 5 Pa (Unloaded via Pirani gauge) |
|
Shelf Temperature Range |
-45°C to +65°C |
-50°C to +70°C |
-50°C to +70°C |
|
Shelf Temperature Uniformity |
±1°C (Across active surface) |
±1°C (Across active surface) |
±1°C (Across active surface) |
|
Effective Shelf Area & Layout |
0.12 m² (2 Shelves + 1 Pre-freeze shelf) |
0.18 m² (3 Shelves) |
0.30 m² (4 Shelves) |
|
Refrigeration System |
Dual-stage cascade; CFC-free refrigerants (R404A/R23) |
Dual-stage cascade; CFC-free refrigerants (R404A/R23) |
Dual-stage cascade; CFC-free refrigerants (R404A/R23) |
|
Chamber & Shelf Material |
304 Stainless Steel (316L contact optional) |
304 Stainless Steel (316L contact optional) |
304 Stainless Steel (316L contact optional) |
|
Control System Interface |
7-inch industrial PLC touchscreen (32 program segments) |
7-inch industrial PLC touchscreen (32 program segments) |
7-inch industrial PLC touchscreen (32 program segments) |
|
Electrical & Safety Standards |
220V/50Hz or 110V/60Hz; CE & UL/CSA/ETL compliant |
220V/50Hz or 110V/60Hz; CE & UL/CSA/ETL compliant |
220V/50Hz or 110V/60Hz; CE & UL/CSA/ETL compliant |
Applications
Pharmaceutical Formulations: Vaccines, monoclonal antibodies, and small-molecule APIs targeting extended shelf life without cold chains.
Biotechnology: Enzymes, diagnostic reagents, and blood plasma derivatives.
Material Science: Porous nanomaterials, aerogels, and polymer scaffolds.
Botanical & Food R&D: Thermal stabilization of heat-sensitive active metabolites and antioxidants.
Selection Criteria
Collapse Temperature (Tc): Formulations with low eutectic points require -80°C units (BL-18B / BL-30C) to ensure complete freezing prior to primary drying.
Solvent Compatibility: Aqueous-organic mixtures demand chemical-resistant pump upgrades and PTFE-coated chamber internals.
Vial vs. Bulk: Vial processing requires pneumatic stoppering mechanisms; bulk processing utilizes standard open trays.
Customization Options
Vial Stoppering System: Pneumatic under-vacuum sealing assembly for automated or manual cap closure of glass vials prior to chamber release.
Defrosting Utility: Integrated electric or hot-gas quick-defrosting mechanism to minimize downtime between batches.
Compliance Software: CFR 21 Part 11 compliant audit trail packages configured for pharmaceutical GMP validation and data security protocols.
Manifold Attachments: Specialized multi-port external valve fittings designed for flask, serum bottle, and ampoule drying alongside standard tray processing.
Quality Control Protocols
Material Traceability: 316L stainless steel product contact surfaces; 304 structural frames.
Pressure Testing: Helium mass spectrometer leak detection on all vacuum chambers and refrigeration circuits.
Electrical Verification: High-voltage insulation resistance testing meeting international safety standards.
Factory Acceptance Testing (FAT): 48-hour continuous verification recording pull-down times and thermal stability curves.
Packaging & Logistics
Crate Spec
Fumigation-free plywood crate with moisture barrier foil and high-density EPE shock absorption.
Standard Inclusions
Vacuum pump, oil mist trap, KF-25 stainless steel bellows, spare gaskets, and operation manuals.
Lead Time
2 to 3 weeks for standard builds. Air and ocean freight terms (FOB/CIF/DDP) supported.
After-Sales Support
Documentation Dossier: Complete English technical package including electrical schematics, P&ID diagrams, FAT test reports, and factory calibration certificates.
Hardware Warranty: Standard 12-month coverage protecting core refrigeration compressors, vacuum pumps, and PLC control modules against manufacturing defects.
Remote Engineering: Secure digital diagnostic channels providing direct engineering assistance for parameter troubleshooting and firmware updates.
Spare Parts & Maintenance: Readily available inventory of replacement gaskets, oil mist filters, and vacuum bellows dispatched within 48 hours to minimize lab downtime.
Frequently Asked Questions
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