Compact Benchtop Freeze Dryer

Compact Benchtop Freeze Dryer

Benchtop freeze dryers provide controlled sublimation for heat-sensitive biologicals, pharmaceuticals, and analytical samples within limited laboratory footprints. Combining compact table-top dimensions with industrial-grade cascade refrigeration and high-vacuum architecture, these units ensure reliable sample reconstitution, prolonged shelf-life, and precise moisture removal for R&D laboratories, university research units, and pilot-scale processing.
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Description
Technical Parameters

Benchtop freeze dryers provide controlled sublimation for heat-sensitive biologicals, pharmaceuticals, and analytical samples within limited laboratory footprints. Combining compact table-top dimensions with industrial-grade cascade refrigeration and high-vacuum architecture, these units ensure reliable sample reconstitution, prolonged shelf-life, and precise moisture removal for R&D laboratories, university research units, and pilot-scale processing.

 

Product Range

 

 

Model Series

Condenser Temp.

Ice Capacity (24h)

Shelf Config. & Area

Primary Application

FD-1A (Standard)

-50°C

1.0 L

4 Tiers (0.12 m2, Acrylic Chamber)

General biological samples, aqueous solutions, bulk materials

FD-2C (Stoppering)

-50°C / -80°C

2.0 L

3 Tiers with Pneumatic Stoppering (0.15 m2)

Pharmaceutical vials, serum, sealing under vacuum

FD-4T (Manifold/Multi-port)

-80°C

3.0 L

Flasks + Internal Shelves (0.10 m2)

Botanical extracts, low eutectic point solvents, ampoules

 

Technical Specifications & Compliance

 

 

Technical Parameter

Standard / Configuration A (General Lab)

Advanced / Configuration B (Low Eutectic)

Model Series Match

FD-1A (Standard)

FD-2C / FD-4T

Condenser Temperature

-50°C (CFC-free cascade refrigeration system)

-80°C (Dual-compressor cascade system)

Ultimate Vacuum

<5 Pa (0.05 mbar) clean and dry system

<5 Pa (0.05 mbar) clean and dry system

Ice Condenser Capacity

1.0 L / 24h (tested at ambient 20°C)

Up to 3.0 L – 4.0 L / 24h

Product Chamber Material

316L stainless steel base with high-transparency acrylic bell jar

316L stainless steel base with 304 stainless steel cylindrical chamber

Condenser Coil / Collector

Seamless 304 stainless steel, internal serpentine configuration

Seamless 304 stainless steel, anti-corrosion finish

Control Architecture

7-inch industrial PLC touchscreen interface; real-time graphical curve display; USB audit-trail data export

7-inch industrial PLC touchscreen interface; real-time graphical curve display; USB audit-trail data export

Power Supply Requirements

220V/50Hz or 110V/60Hz (configurable)

220V/50Hz or 220V/60Hz (high-load electrical layout)

Safety & Quality Standards

CE Marked, ISO 9001 Quality Management Compliant

CE Marked, ISO 9001 Quality Management Compliant

Electrical Component Standard

Built to UL/CSA compliant component specifications

Built to UL/CSA compliant component specifications

 

Applications

 

 

Biopharmaceuticals: Lyophilization of proteins, peptides, live vaccines, and diagnostic reagents to prevent thermal degradation.


Botanical & Herbal Extraction: Preservation of heat-sensitive active pharmaceutical ingredients (APIs) and delicate organic compounds.


Material Science: Drying of nanomaterials, polymers, and porous catalysts to preserve micro-porous structural integrity.


Environmental & Food Testing: Preparation of biological tissue samples, marine extracts, and reference standards for trace analysis.

 

Selection Guide

 

 

Selecting the correct benchtop lyophilizer requires evaluating four core parameters:


Solvent Eutectic Point: Choose -50°C condensers for standard aqueous solutions; select -80°C units for solvents containing low-freezing-point organic modifiers (e.g., tert-butanol, acetonitrile) to prevent melt-back.


Sample Container Type:
Bulk trays/beakers:
Standard manifold or open shelf configuration.
Vials requiring sealing: Pneumatic stoppering shelf assembly to seal rubber stoppers under vacuum prior to chamber release.


Total Batch Volume: Match the 24-hour ice condensation rate (L/24h) to the total water weight per batch, ensuring condenser capacity exceeds total sample moisture load by at least 30%.


Vacuum Pump Displacement: Ensure rotary vane pump displacement (2 L/s to 4 L/s) matches chamber volume to achieve target ultimate vacuum within 15 minutes.

 

Customization Options

 

 

Manifold Configurations: Custom rubber valve ports (side-mounted) for round-bottom flasks, ampoules, and serum bottles.


Defrost Mechanism: Electric quick-defrost or hot-gas bypass integration to minimize turnaround time between batches.


Sensor Integration: Optional Pirani vacuum gauge for precise low-pressure measurement and eutectic point determination.


Voltage & Plug Standards: Customized electrical configurations tailored to regional grid standards.

 

Quality Control

 

 

Pressure Vessel Testing: Every stainless steel condenser and chamber undergoes helium mass spectrometer leak testing down to 10^-9 Pa·m3/s.


Refrigeration Run-Test: 72-hour continuous burn-in test at maximum thermal load to verify compressor stability, oil return, and temperature pulldown rates.


Electrical Safety Inspection: Dielectric strength test (1500V/1min) and grounding continuity verified per international electrical safety standards.


Traceability: Individual serial numbers tracking raw material mill test certificates (MTCs) and component calibration logs.

 

Packaging & International Shipping

 

 

Export Packaging: Fumigation-free plywood crates lined with internal EPE shock-absorbing foam and moisture-barrier vacuum-sealed foil bags.


Accessory Separation: Vacuum pumps, glass chambers, and delicate acrylic covers packed in distinct sub-cartons to eliminate transit damage.


Documentation Included: Bill of Lading, Commercial Invoice, Packing List, CE Declaration of Conformity, Factory Inspection Report, and Operation Manual in English.

 

Technical Support & After-Sales Service

 

 

Warranty: 12-month standard warranty covering core mechanical and electrical components (compressors, vacuum pumps, and controllers).


Remote Diagnostics: Video-guided troubleshooting and firmware updates handled by experienced laboratory equipment engineers.


Spare Parts Availability: Critical wear items (vacuum pump oil, silicone door gaskets, KF clamps, and centering rings) stocked for dispatch within 48 hours.

 

Frequently Asked Questions

 

 

Q: What is the operational difference between a -50°C and -80°C condenser?

A: -50°C units suit standard water-based solutions. -80°C dual-compressor systems reach lower temperatures required for samples with low eutectic points or organic co-solvents that remain liquid at -40°C.

Q: Do I need an external oil mist filter for the vacuum pump?

A: Yes. All standard packages include an exhaust oil mist filter to capture pump oil vapor, maintaining clean laboratory air quality.

Q: Can this unit handle acidic or corrosive solvents?

A: Standard units feature 304/316L stainless steel, but strong acids require specialized PTFE-coated chambers and chemical-resistant diaphragm pumps. Specify your solvent composition when inquiring.

Q: What routine maintenance is required for daily operation?

A: Drain and defrost the ice condenser completely after each cycle, wipe the chamber dry, check vacuum pump oil level and clarity, and inspect door seals for particulate contamination.

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