Category Overview
Laboratory freeze dryers for research and development provide precise thermodynamic control, shelf temperature profiling, and deep vacuum capability for small-batch lyophilization. These units establish critical primary and secondary drying parameters-such as collapse temperature and desorption rates-prior to scale-up into production-tier equipment.
Product Range
Benchtop Series (1L - 4L Capacity): Compact footprints for standard aqueous samples and academic research. Configurations include ambient-to--50°C and cold-trap -80°C setups.
Pilot Upright Series (6L - 12L Capacity): Multi-shelf configurations featuring individual shelf heating and pneumatic stoppering systems for small-vial pharmaceutical R&D.
Organic Solvent Resistant Series: Equipped with chemically resistant vacuum pumps, fluorocarbon seals, and solvent-safe chambers for volatile formulations like acetonitrile or trifluoroacetic acid (TFA).
Technical Specifications
|
Model Series |
Condenser Temp. |
Ultimate Vacuum |
Ice Condenser Capacity |
Shelf Temp. Range |
Defrost Method |
|
FD-10A (Benchtop) |
<= -50°C |
< 5 Pa |
4 kg / 24h |
-50°C to +70°C |
Ambient Heat |
|
FD-12B (Pilot Stoppering) |
<= -80°C |
< 1 Pa |
8 kg / 24h |
-55°C to +70°C |
Hot Gas Defrost |
|
FD-18C (Organic Solvent) |
<= -80°C |
< 0.5 Pa |
12 kg / 24h |
-60°C to +80°C |
Electric Heater |
Refrigeration: Hermetic compressors with CFC-free mixed refrigerants (R404A / R507 / R23); dual-stage cascade cooling for -80°C models.
Control Interface: 7-inch industrial PLC touchscreen with real-time curve logging, USB data export, and 36-segment program storage.
Chamber Build: 304/316L stainless steel seamless welded vessel with electropolished interior (Ra <= 0.4 um).
Applications
Pharmaceutical R&D: Lyophilization cycle development for monoclonal antibodies, vaccines, and small-molecule injectables. (Typical primary/secondary drying cycle: 24 to 48 hours based on fill depth).
Life Sciences: Preservation of bacterial strains, viral vectors, enzymes, and blood plasma fractions.
Material Science: Synthesis of porous aerogels, ceramic nanoparticles, and polymer scaffolds requiring isotropic pore structures.
Food & Agriculture: Extraction of heat-sensitive botanical actives and reference standard preparation.
Selection Guide
Eutectic / Collapse Temperature: Formulations containing high salt or sugar concentrations require -80°C condensers to prevent micro-collapse during primary drying.
Solvent Chemistry: Aqueous samples utilize standard acrylic chambers. Organic co-solvents require stainless steel vessels, FKM gaskets, and chemical trap accessories.
Vessel vs. Bulk Configuration: Use flask manifolds for loose bulk samples in round-bottom flasks. Use heated shelves with stoppering capability for controlled vial processing.
Customization Options
Stoppering Systems: Pneumatic or hydraulic bottom/top mechanisms for vacuum-sealing vials internally.
Vacuum Regulation: Proportional solenoid valve integration for precise barometric pressure control during primary drying.
Sensor Integration: Pt100 product temperature probes and Pirani/Capacitance dual-range manometers.
Software Compliance: Optional 21 CFR Part 11 compliant audit trail packages for regulated labs.
Quality Control & Compliance
Regulatory Standards: Built under ISO 9001 quality systems; electrical and mechanical safety certified to CE and RoHS directives.
Helium Leak Testing: Mass spectrometer testing on all refrigeration coils and vacuum chambers ensuring leak rates < 1 x 10^-7 Pa*m^3/s.
Temperature Mapping: Multi-point thermocouple testing verifying shelf-to-shelf temperature deviation within +/- 1.0°C.
Burn-in Testing: 72-hour continuous operational test under maximum load prior to crating.
Packaging & International Shipping
Crates: Fumigation-free plywood export boxes lined with moisture-barrier vacuum foil and shock-absorbing EPE foam.
Documentation: English user manual, wiring schematics, refrigeration piping diagrams, factory calibration certificates, CE declaration of conformity, and 3.1 material traceability certificates upon request.
Logistics: EXW, FOB, CIF, or DDP terms via specialized air and ocean freight forwarders.
Technical Support & After-Sales Service
Commissioning Support: Video-guided installation manuals and direct remote engineering assistance.
Warranty: 12-month standard coverage on mechanical and electrical components, including compressors and PLC controllers.
Spare Parts: Critical wear items (vacuum pump oil, exhaust filters, door seals) stocked for rapid dispatch.
Frequently Asked Questions
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