Desktop Vacuum Lyophilizer

Desktop Vacuum Lyophilizer

A desktop vacuum lyophilizer removes moisture from frozen samples via sublimation under controlled vacuum and temperature, bypassing the liquid phase to preserve biological potency and structural integrity. Designed for space-constrained labs, these compact units integrate commercial refrigeration cascades, dual-stage rotary vane vacuum pumps, and PLC controls. Systems comply with CE electrical directives and utilize ozone-friendly refrigerants (R290/R404A).
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Description
Technical Parameters

A desktop vacuum lyophilizer removes moisture from frozen samples via sublimation under controlled vacuum and temperature, bypassing the liquid phase to preserve biological potency and structural integrity.


Designed for space-constrained labs, these compact units integrate commercial refrigeration cascades, dual-stage rotary vane vacuum pumps, and PLC controls. Systems comply with CE electrical directives and utilize ozone-friendly refrigerants (R290/R404A).

 

Product Range

 

 

Model Series

Ice Condenser Capacity

Ultimate Vacuum

Condenser Temperature

Shelf Configuration

Primary Application

DT-10A

1 L / 24 h

< 10 Pa

-50 deg C

4 Trays (Upright Acrylic Chamber)

Routine biological samples, botanical extracts

DT-20V

2 L / 24 h

< 5 Pa

-50 deg C or -80 deg C

3 Heated Shelves + Stoppering

Pharmaceutical vials, peptide sealing

DT-40T

4 L / 24 h

< 1 Pa

-80 deg C

4 Heated Shelves (Manifold + Tray combo)

Multi-user lab, organic solvent removal

 

Technical Specifications

 

 

Technical Parameter

Standard Specification (DT-10A / DT-20V)

Deep-Cooling & Custom Option (DT-40T / Custom)

Condenser Temperature

-50 deg C

-80 deg C (For low eutectic point solvents)

Ultimate Vacuum Level

< 5 Pa (Empty chamber, Pirani gauge)

< 1 Pa (High-vacuum configurations)

Chamber Construction

316L Stainless Steel cylinder with 20mm transparent acrylic door

All-316L Stainless Steel (Optimized for organic solvents)

Refrigeration System

Hermetic SECOP / Danfoss compressors (CFC-free R404A)

Dual-stage cascade refrigeration (CFC-free R290/R508B)

Control Interface

7-inch industrial true-color touch screen (36 programs / 36 segments)

PLC + Touch screen with SCADA / USB data export

Defrost Method

Electric heating rapid defrost (<= 15 mins)

Electric heating rapid defrost

Power Requirements

220V +/- 10 percent, 50/60 Hz

Customizable 110V or regional variants

Safety Compliance

CE Certified, IEC 61010-1 Electrical Safety, ISO 9001 Factory QC

CE Certified, ISO 9001, Helium leak-tested

 

Applications

 

 

01/

Protein & Vaccine Preservation: Stabilizing labile biological macromolecules without thermal degradation.

02/

Vial Stoppering: Pneumatic stoppering mechanism seals glass serum vials under vacuum prior to release.

03/

Organic Chemistry & Nanotechnology: Removing high-boiling-point solvents (DMSO, acetonitrile) via cold traps.

04/

Food & Agricultural R&D: Small-batch pilot drying of functional food powders and plant metabolites.

 

Selection Guide

 

 

Condenser Temperature Matching:
50 deg C:
For aqueous solutions, standard biological buffers, and plant extracts.


80 deg C: For low-concentration methanol, ethanol, or low eutectic point salts.


Configuration Selection:
Manifold Units:
For round-bottom flasks, ampoules, and serum bottles processed concurrently.


Tray Shelves: For bulk petri dish drying or batch vial processing.


Vacuum Pump Sizing: Match displacement rate to chamber volume (2 L/s to 4 L/s); ensure anti-suckback and oil mist filtration.

 

Customization Options

 

 

Solvent Resistance: PTFE-coated condenser coils and chemical-resistant diaphragm/hybrid vacuum pumps.


Data Logging: USB export and Ethernet ports for SCADA integration in GMP environments.


Inert Gas Backfilling: Solenoid valve integration for post-drying nitrogen or argon purging.


Chamber Dimensions: Custom shelf spacing for non-standard sample holders.

 

Quality Control

 

 

Manufacturing Standards: ISO 9001 certified production.


Leak Detection: Helium mass spectrometer testing on every welded refrigeration and vacuum circuit.


Thermal Mapping: 9-point shelf temperature verification via calibrated thermocouples.


Electrical Safety: High-voltage dielectric withstand and earth continuity per IEC 61010-1.


Burn-in Testing: 72-hour continuous run under full vacuum and load prior to packaging.

 

Packaging & International Shipping

 

 

Crate Structure: Fumigation-free plywood crates with moisture-barrier film and EPE foam shock absorbers.


Component Separation: Vacuum pump shipped in an independent reinforced carton to prevent dynamic transit shock.


Export Documentation: Certificate of Origin, 316L Material Test Reports, CE Declaration, ISO 9001 statement, and English manuals.

 

Technical Support & After-Sales Service

 

 

Warranty

2-year coverage on compressors, control boards, and vacuum components.

 

Diagnostics

Video-guided troubleshooting and remote firmware updates by factory application engineers.

 

Consumables

Local stock of vacuum pump oil, exhaust filters, and door gaskets for rapid dispatch.

 

 

Frequently Asked Questions

 

 

Q: What is the maximum moisture load per batch?

A: Moisture load must not exceed 80 percent of the 24-hour ice condenser capacity (e.g., max 1.6L for a 2L model) to prevent vapor breakthrough.

Q: Is an external cold trap required for organic solvents?

A: Yes, low-freezing-point solvents require a -80 deg C system paired with a solvent trap to protect pump oil.

Q: What is the recommended vacuum pump oil replacement interval?

A: Every 300 operating hours for standard aqueous operations. High particulate or solvent usage requires frequent inspection.

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